The Science

4,000+ studies. One molecule. The signal your skin is missing.

CUPRESSE Serum with GHK-Cu

What Is GHK-Cu?

GHK-Cu (Copper Tripeptide-1) is a naturally occurring peptide in human blood plasma. It consists of three amino acids — glycine, histidine, and lysine — bound to a copper ion.

Discovered in 1973 by Dr. Loren Pickart, GHK-Cu acts as a biological signal that tells your cells to produce collagen, elastin, and glycosaminoglycans — the building blocks of firm, hydrated skin.

At age 20, your blood contains approximately 200 ng/mL of GHK-Cu. By age 60, that drops below 80 ng/mL — a 60%+ decline that directly correlates with visible aging.

4,000+
Published Studies
70%
Collagen Increase
60%
GHK-Cu Lost by Age 60
1973
Year Discovered
CUPRESSE Facial Cream

How GHK-Cu Works

Unlike retinol, which forces skin cell turnover (often causing irritation, redness, and barrier damage), GHK-Cu works with your skin's natural biology.

When applied topically, GHK-Cu:

1. Signals collagen production — activates genes responsible for collagen I and III synthesis, increasing skin thickness and density.

2. Repairs the skin barrier — stimulates production of glycosaminoglycans (including hyaluronic acid), strengthening the moisture barrier.

3. Reduces inflammation — suppresses pro-inflammatory cytokines, calming redness and sensitivity.

4. Acts as an antioxidant — neutralizes free radical damage from UV exposure and pollution.

The 3-Layer Delivery System

Each product in The Copper Renewal Ritual is designed for a specific step — together, they amplify GHK-Cu's effects across your entire body.

1
Facial Serum
Signal

Facial Serum

Concentrated GHK-Cu penetrates deep into skin layers. The lightweight serum delivers the copper signal directly to cells that produce collagen.

2
Facial Cream
Seal

Facial Cream

Barrier-repair moisturizer with squalane and Pro-Vitamin B5. Seals in the copper signal while rebuilding the moisture barrier.

3
Body Cream
Firm

Body Cream

Extends GHK-Cu to neck, chest, arms, and body. Shea butter and squalane deliver the copper signal to areas most routines ignore.

Key Ingredients

GHK-Cu (Copper Tripeptide-1)

The hero molecule. Signals collagen synthesis, repairs skin barrier, reduces inflammation. 4,000+ published studies.

Squalane

Plant-derived lipid identical to your skin's natural sebum. Deep hydration without clogging pores. Strengthens the moisture barrier.

Pro-Vitamin B5 (Panthenol)

Accelerates skin healing and barrier repair. Improves hydration, softness, and elasticity while reducing transepidermal water loss.

Hyaluronic Acid

Holds 1,000x its weight in water. Multi-weight formula hydrates surface and deep layers simultaneously for plump, dewy skin.

Shea Butter

Rich in vitamins A, E, and F. Provides deep nourishment and creates a protective layer that locks in moisture and active ingredients.

Vitamin E (Tocopherol)

Potent antioxidant that protects against UV and environmental damage. Works synergistically with GHK-Cu to reduce oxidative stress.

Free From

No Retinol No Parabens No Artificial Fragrance No Sulfates No Drying Alcohols

Give Your Skin the Signal Back

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